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Middle-aged women getting mammograms despite guidelines

Wednesday May 15, 2013
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Women in their 40s continue to undergo routine breast cancer screenings despite national guidelines recommending otherwise, according to a study.

In 2009, the U.S. Preventive Services Task Force recommended that while women ages 50 to 74 should continue to undergo mammograms every two years, those between the ages of 40 and 49 without a family history of breast cancer should discuss the risks and benefits of routine screening mammography with their physicians to make individual decisions.

As a result of the altered recommendations, Lauren D. Block, MD, MPH, a clinical fellow at the Johns Hopkins University School of Medicine, and her colleagues expected to find fewer women in their 40s getting routine mammograms. Instead, they found no impact on mammography rates among younger women.

"Patients — and likely their providers — appear hesitant to change their behavior, even in light of evidence that routine screening in younger women carries substantial risk of false positives and unnecessary further imaging and biopsies," Block said in a news release. "Women have been bombarded with the message 'mammograms save lives,í so they want them no matter what."

Previous research has shown mammographyís impact on younger women is mixed at best, according to the news release: Routine screening increases rates of detecting cancer in young women, but reduces mortality risk by a very small percentage. It is more likely, studies have shown, to result in over-diagnosis and unnecessary treatment, including biopsies, lumpectomies and mastectomies, and weeks of radiation and potentially toxic drugs. False positives result in avoidable procedures and psychological trauma. Many of the cancers detected probably will never be dangerous, but are aggressively treated.

Among older women, screening mammograms are recommended because breast cancer, like most cancer, is a disease of aging, and a womanís risk of breast cancer increases as she grows older.

The original USPSTF guideline change recommended more forcefully against routine screening for women in their 40s, but a political and advocacy group backlash resulted in compromise language that counseled individual decision-making by patients and physicians, the Hopkins researchers noted. The American Cancer Society continues to recommend yearly mammography for women starting at age 40.

Moreover, Block said, insurance companies continue to pay for routine mammograms for women in their 40s. That trend is a likely reason for the persistently high rate of screening.

As published on the website of the Journal of General Internal Medicine, Block and her colleagues analyzed mammogram use data from Behavioral Risk Factor Surveillance System surveys administered in 2006, 2008 and 2010 by state health departments nationwide. Data from 484,296 women ages 40 to 74 were collected. Among women in their 40s, 53% reported having a mammogram in the past year in 2006 and 2008, compared with 65% of women ages 50 to 74. In 2010, after the new recommendations had been in effect, 52% of younger women and 62% of older women reported having a mammogram.

The USPSTF recommendations also stated there is no benefit to screening women who are older than 75 and at normal risk of breast cancer.

Block said she sees the same reluctance among her 40-something patients to change course on mammography when she has the conversations about the pros and cons. Some of her patients are relieved that they can postpone mammography until age 50, but many more want to continue being screened.

"Breast cancer gets so much attention in the media and in society in general, despite cardiovascular disease being by far the number one killer in women," Block said. "Everyone wants to feel as though they are preventing breast cancer. You hear one anecdotal story about someone in their 40s who found cancer during a mammogram and did really well with treatment, and thatís enough to fly in the face of any other facts that are out there. Women want the test."

Read the study abstract: http://link.springer.com/article/10.1007/s11606-013-2482-5.


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