People with sleep apnea appear to be at higher risk of pneumonia, according to a study.
Sleep apnea is characterized by disrupted sleep, caused when the upper airway becomes obstructed by soft tissue, cutting off oxygen. It has been linked to several types of heart disease and cognitive impairment. People with obstructive sleep apnea are at higher risk of aspiration while sleeping.
To determine whether sleep apnea is linked to the development of pneumonia, Taiwanese researchers followed 34,100 patients (6,816 who had sleep apnea and 27,284 controls) for 11 years. They found that pneumonia was more likely to develop in the people with sleep apnea than in the control group, with 638 pneumonia cases in the sleep apnea group (9.36%) and 2,119 in the control group (7.77%). The people with pneumonia were older and had more comorbidities such as heart disease, diabetes, dementia and other diseases.
This study showed that sleep apnea is an independent risk factor for incident pneumonia, researchers with Taipei Veterans General Hospital wrote March 3 on the website of the Canadian Medical Association Journal.
Our results also demonstrated an exposure-response relationship in that patients with more severe sleep apnea may have a higher risk of pneumonia than patients with sleep apnea of milder severity.
Several studies have explored the link between sleep apnea and pneumonia, although they have been smaller than this large cohort study, the researchers noted.
The authors suggest the higher incidence of pneumonia in people with sleep apnea could be because of increased risk of aspirating contents or liquid from the throat.