Depression affects more than 1 in 3 survivors of critical illness, according to a study, and the majority of patients experience their symptoms physically rather than emotionally.
The study is one of the largest to investigate the mental health and functional outcomes of critical care survivors, according to lead author James Jackson, PsyD, assistant professor of medicine at Vanderbilt University School of Medicine in Nashville, Tenn., and highlights a significant public health issue, with roughly 5 million patients admitted to ICUs in the U.S. each year.
Weakness, appetite change and fatigue all signs of somatic depression were present in two-thirds of the patients with depression, as opposed to cognitive symptoms such as sadness, guilt or pessimism, researchers reported April 7 on the website of The Lancet Respiratory Medicine.
We need to pay more attention to preventing and treating the physical rather than psychological symptoms of depression in ICU survivors, Jackson said in a news release. The physical symptoms of depression are often resistant to standard treatment with antidepressant drugs, so we need to determine how best to enhance recovery with a new focus on physical and occupational rehabilitation.
The BRAIN-ICU study observed 821 critically ill patients ages 18 to 90 with respiratory failure or severe sepsis who were admitted to medical or surgical ICUs at Vanderbilt University Hospital and Saint Thomas Hospital.
Vanderbilt researchers assessed survivors for depression, PTSD, functional disability and impact on quality of life at three-month and one-year intervals, reporting that 149 of the 407 patients (37%) assessed at three months had at least mild depression, while only 7% experienced symptoms of PTSD.
Depression symptoms were significantly more common than symptoms of PTSD, Jackson said. And they occurred to a large degree across the entire age range. People tend to have a vision of a frail, older patient who goes to the ICU and is at risk for adverse mental health and, in particular, functional outcomes. But what people dont anticipate is someone in their 20s, 30s or 40s could go to the ICU and leave with functional disability, depression or PTSD. These problems are not really a function of old age.
A third of the survivors who developed depression still had depressive symptoms at their one-year assessment, a statistic that Jackson said could be due in part to high expectations they set for rehabilitation.
They have some arbitrary timeline set and they reach that date and theyre still not better and, in some cases, not a lot better at all, he said. Then what can happen is that depression can really worsen because they set this expectation that was really unrealistic and they feel like they have missed the goal.
So thats a big challenge, recalibrating expectations. This is especially hard for the many high-achieving, type-A patients that we might see who leave the ICU and want to get back to work right away, want to compete in the triathlon right away. They tend to have the hardest time.
Jackson said study authors gained additional perspective on their patients by doing at-home assessments following discharge. One thing we learned was that if people dont have significant social support, they are profoundly limited in their ability to access care or improve in key areas, he added.
Study abstract: http://bit.ly/1hTGqiD